Phospho stat1
WebSTAT1 is known to regulate several genes which are involved in cell growth, apoptosis, immune responses, and lipid metabolism. Further, STAT1 plays an important role in mediating cell viability in response to different cell stimuli and pathogen exposure. The STAT1 gene is located on chromosome 2. WebSTAT1 is known to regulate several genes which are involved in cell growth, apoptosis, immune responses, and lipid metabolism. Further, STAT1 plays an important role in mediating cell viability in response to different cell stimuli and pathogen exposure. The STAT1 gene is located on chromosome 2.
Phospho stat1
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WebMar 21, 2024 · STAT1 (Signal Transducer And Activator Of Transcription 1) is a Protein Coding gene. Diseases associated with STAT1 include Immunodeficiency 31C and Immunodeficiency 31B . Among its related pathways are IL-9 Signaling Pathways and Prolactin Signaling . Gene Ontology (GO) annotations related to this gene include DNA … WebApr 14, 2024 · The transcription factor STAT1 plays an essential role in antiviral innate immunity in the response to type I and III IFNs. Next, we examined the activation of …
WebA phospho specific peptide corresponding to residues surrounding Serine 727 of human Stat-1 was used as an immunogen. This antibody only detects Stat-1 phosphorylated at Serine 727. Tested applications Suitable for: WB, … WebMar 31, 2024 · Crystallographic studies of STAT1 have elucidated its modular structure, comprised of six domains, namely (1) an N-terminal domain, (2) a coiled-coil domain, (3) a …
WebMar 31, 2024 · Background: Unphosphorylated signal transducer and activator of transcription 1 (U-STAT1) has been reported to elicit a distinct gene expression profile as compared to tyrosine-phosphorylated STAT1 (P-STAT1) homodimers. However, the impact of U-STAT1 on the IFNγ-induced immune response mediated by P-STAT1 is unknown. By … WebSTAT1 is known to regulate several genes which are involved in cell growth, apoptosis, immune responses, and lipid metabolism. Further, STAT1 plays an important role in mediating cell viability in response to different cell stimuli and pathogen exposure. The STAT1 gene is located on chromosome 2.
WebPhospho‑STAT1 expression as a potential biomarker for anti‑PD‑1/anti‑PD‑L1 immunotherapy for breast cancer Phospho‑STAT1 expression as a potential biomarker for anti‑PD‑1/anti‑PD‑L1 immunotherapy for breast cancer Authors
WebNov 29, 2024 · IFN-I is the key regulatory component activating and modulating the response of innate and adaptive immune system to bacterial as well as viral pathogens. IFN-I promotes the expression of IFN-induced genes (ISG) and, consequently, the production of chemokines, e.g., CXCL10. Those chemokines control migration and localization of … church set up team ministryWebJun 28, 2024 · p-Stat1 Antibody (A-2) is an IgG1 κ mouse monoclonal p-Stat1 antibody suitable for the detection of Stat1 phosphorylated at Tyr 701 of mouse, rat and human origin by WB, IP, IF, FCM and ELISA. p-Stat1 Antibody (A-2) is available as the non-conjugated anti-p-Stat1 antibody form, as well as multiple conjugated forms of anti-p-Stat1 … church sextonWebMar 31, 2024 · STAT1 is localized predominantly in the cytoplasm prior to cytokine stimulation and upon receptor activation by IFNγ, the receptor-associated JAKs phosphorylate a critical tyrosine residue at position 701 in the STAT1 transactivation domain producing phosphorylated STAT1 (P-STAT1). dew lightsWebSTAT1, also known as signal transduction and activator of transcription 1, is a ubiquitously expressed cytoplasmic protein and is activated in response to cytokine signaling, including IFN-α, IFN-γ, EGF, PDGF, and IL-6. church sexton contractWebSee all STAT1 primary antibodies Description Mouse monoclonal [M135] to STAT1 (phospho Y701) Host species Mouse Specificity The antibody detects 84 and 91 kDa … church sexton definitionWebSTAT1 Phospho (Tyr701) A17012A : ICFC, ICC, WB, ChIP: STAT1 Phospho (Ser727) A15158B : ICFC, ICC, WB, ChIP: STAT3 Phospho (Ser727) A16089B : ICFC, WB, ChIP: Need a control for your phospho flow cytometry staining? Our Veri-Cells™ Phospho PBMCs can be used as a positive and negative control for staining members of the MAPK/ERK pathway. dewlish churchWebSTAT1 is activated to regulate gene expression in response to extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STAT1 enters the nucleus … dew line in canada