Ovarian granulosa cell apoptosis

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August undefined, 2024

WebNov 17, 2024 · Oxidative stress leads to ovarian functional decline by inducing granulosa cell (GC) apoptosis. Circular RNA circFoxo3 acts as a critical factor in regulating cell cycle and apoptosis, and ... WebJul 26, 2024 · Primary rat ovarian granulosa cells (OGCs) were collected from ovarian tissues and identified by cell immunohistochemistry. The effects of miR-126-3p-hucMSCs-exosomes and miR-126-3p on OGCs function were determined by cell proliferation and apoptosis assays in a cisplatin induced POF cell model.

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WebJun 1, 2024 · Section snippets Cell lines and cell culture. Human ovarian granulosa cell line (KGN cell) was obtained from Prof. Jiangning Zhou as a gift. In previous studies, … WebNov 21, 2024 · Bax-dependent apoptosis is a common pathway of cell death and the balance of Bcl-2 and Bax is a key determinant of the survival or death of GCs. As expected, the level of Bcl-2 and the ratio of Bcl-2/Bax were found to be markedly reduced after down-regulation of GPSM1. growing a non gmo crop

Mir-484 contributes to diminished ovarian reserve by regulating ...

WebApr 11, 2024 · This may be because full-term PPE promotes the proliferation of pre-granulosa cells, while mid-late pregnancy exposure inhibits apoptosis of pre … WebJan 29, 2024 · Ovarian follicles are structures generated in the ovaries and have two major functions, the production of hormones and oocytes. Antral follicles regulate these functions via the inner wall of granulosa cells (GCs) that rest on a distinct basal lamina. Ovarian follicles are made up of oocytes surrounded by pre-granulosa cells or GCs. WebNov 8, 2024 · Ambient particulate matters (PMs) have adverse effects in human and animal female reproductive health. Silica nanoparticles (SNPs), as a major component of PMs, can induce follicular atresia via the … film style photo frame

Growth hormone protects against ovarian granulosa cell …

Autophagy in Ovarian Follicular Development and Atresia - PMC

WebDec 23, 2024 · Granulosa cells apoptosis happens by the omission of miR-21 through particular inhibitors; therefore miR-21 acts for granulosa cells maintenance in the follicles prior to the ovulation [ 41 ]. Notably, in vivo miR-21 action blockade through using blocking oligonucleotide into the ovarian bursa stopped ovulation [ 9, 41 ]. WebJun 1, 2024 · Human ovarian granulosa cell line (KGN cell) was obtained from Prof. Jiangning Zhou as a gift. In previous studies, KGN cell line was considered as a very useful model that mimicked the physiological regulation of steroidogenesis, cell growth, and apoptosis in human granulosa cells [29, 30]. film style with a french name crossword clueWebApr 10, 2024 · Furthermore, both APLN-13 and -17 improved the total antioxidant capacity of the ovarian granulosa cells, but such effects were not seen when the cells were … films \u0026 tv app download

"WebApr 11, 2024 · This may be because full-term PPE promotes the proliferation of pre-granulosa cells, while mid-late pregnancy exposure inhibits apoptosis of pre-granulosa cells, thus affecting the expression of CYP19 in fetal ovarian pre-granulosa cells. However, the specific mechanism needs to be further explored. " - Ovarian granulosa cell apoptosis

Ovarian granulosa cell apoptosis

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WebJan 9, 2014 · Aberrant ovarian granulosa cell proliferation and apoptosis may lead to granulosa cell tumors (GCT), the pathogenesis of which involves transcription factors … WebFeb 24, 2016 · Granulosa cell (GC) apoptosis has been shown to be involved in follicular atresia, which is a degenerative process in ovarian follicles of mammals. However, the …

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WebApr 1, 2024 · These results demonstrated that PS MPs could induce pyroptosis and apoptosis of ovarian granulosa cells via the NLRP3/Caspase-1 signaling pathway maybe triggered by oxidative stress. The present ... WebApr 10, 2024 · Furthermore, both APLN-13 and -17 improved the total antioxidant capacity of the ovarian granulosa cells, but such effects were not seen when the cells were preincubated with ML221. ... Literature demonstrated that APLN restrains cell apoptosis and retina angiogenesis and improves the proliferation of vascular smooth muscle cells, …

WebThe main characteristic of follicle atresia is the apoptosis of oocytes, granulosa cells and theca cells. ... Tang X, Ma L, Guo S, Liang M, Jiang Z. High doses of FSH induce autophagy in bovine ovarian granulosa cells via the AKT/mTOR pathway. Reprod Domest Anim. 2024; 56:324–32. [Google Scholar] 21. WebApr 11, 2024 · In vivo studies revealed that ADSCs transplantation reduced the apoptosis of ovarian granulosa cells and secretion of follicle-stimulating hormone. The number of total follicles, primordial follicles, primary follicles, and mature follicles and secretion of anti-Müllerian hormone and estradiol (E2) were also increased by ADSCs.

WebMay 31, 2024 · Human umbilical cord mesenchymal stem cells (huMSCs) can treat primary ovarian insufficiency (POI) related to ovarian granulosa cell (OGC) apoptosis caused by cisplatin chemotherapy.... WebJan 10, 2024 · The regulation of ovarian granulosa cell death by pro-and anti-apoptotic molecules. J Reprod Dev. 2006;52:695–705. Article CAS PubMed Google Scholar Manabe N, Kimura Y, Uchio K, Tajima C, Matsushita H, Nakayama M, Sugimoto M, Miyamoto H. Regulatory mechanisms of granulosa cell apoptosis in ovarian follicle atresia.

WebApr 1, 2024 · Polystyrene microplastics induce pyroptosis and apoptosis of ovarian granulosa cells. • Abstract Microplastics (MPs) considered as a new persistent environmental pollutant could enter into the circulatory system and result in decrease of sperm quantity and quality in mice.

WebOct 26, 2024 · Polycystic ovary syndrome (PCOS) is one of the most incident reproductive endocrine diseases, with a prevalence ranging from 5 to 10% in women of reproductive … film style john wickWebAfter the adoptive transfer of Treg cells overexpressing Peli1 in autoimmune POI mice, the apoptosis rate of ovarian granulosa cells declined. The levels of the inflammatory inhibitors interleukin 10 and transforming growth factor-β as well as the ovarian hormone estradiol were elevated. The number of primordial, primary, secondary, and mature ... growing an onion from scrapsWebMore densely housed mice showed increased serum and local ovarian angiotensin II levels; furthermore, increased angiotensin II levels induced granulosa cell apoptosis in vivo. In rodents, treatment with angiotensin II has been shown to modulate ovarian steroidogenesis in vitro within cultured granulosa and theca cells, causing atresia [ 26 ]. growing an olive tree from seedWebApr 11, 2024 · In vivo studies revealed that ADSCs transplantation reduced the apoptosis of ovarian granulosa cells and secretion of follicle-stimulating hormone. The number of … films \u0026 tv app download in windowsWebNov 20, 2024 · STAT4 targets KISS1 to promote the apoptosis of ovarian granulosa cells Collectively, the STAT4 might directly target at - 305/- 295 region of KISS1 to negatively … growing an onion from a bulbWebJan 1, 2015 · Apoptosis in bovine granulosa cells. (a-1) BGC-1 cell in prophase with a big phagocytized AC (hematoxylin). (a-2 and b2) Apoptosis type B in CPGB cells showing … films type time burtonWebJun 15, 2024 · The exclusive criteria of PCOS women; 1, diagnosed with hyperprolactinemia; 2, abnormal androgen secretion due to adrenal or ovarian tumors; 3, patients with uncorrected thyroid disease; 4, suspected Cushing’s syndrome; 5, using estrogen or oral contraceptives and other hormone drugs in recent one month; 6, using other drugs that … growing another term